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Commercial Spaces

Where to Do Business Downtown


From startups to Fortune 1000 headquarters, Downtown St. Louis is a vibrant business hub. More than 2,300 business and government employers call Downtown home, providing jobs for more than 64,000 employees.

Downtown Business District

Greater Downtown has the largest concentration of office space in the region, which includes 233 office buildings with a total of nearly 27 million square feet of space, accounting for 19% of the metro area’s total office space.

Downtown city skyline with a foreground of mid-rise brick and concrete commercial buildings and taller modern high-rise towers rising behind them under a pale blue sky.

Retail Market

Downtown St. Louis has 3.3 million square feet of retail options in a range of new, old, and mixed-use buildings and sizes supporting various shops, stores, and restaurants. With an 8% vacancy rate and an average rent of $17.43 PSF, Downtown has great affordable spaces available. Download our retail opportunities guide to explore opportunities.

Download the Guide

Elevated view down a tree-lined downtown street flanked by historic brick and stone buildings, with cars moving and parked along the lanes and warm late-afternoon sunlight illuminating distant high-rises.
Connect With Us

Contact the Downtown Team