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Doing Business

A Region on the Rise

By the Numbers

With a 2.5% rate of GDP growth, St. Louis ranks 16th among the country’s largest metropolitan areas, well ahead of the region’s population ranking of 23.

23
LARGEST

U.S. METRO

2.8
MILLION

METRO POPULATION

$210
BILLION

GDP

1.5
MILLION

WORK FORCE

Stylized blue-outlined map showing counties around St. Louis labeled with names and a winding river through the center.

15 COUNTIES. ONE REGION.

From rolling farmland to vibrant industry, explore the seven counties in Missouri and eight in Illinois that comprise the St. Louis metro’s diverse economy.

 

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OUR WORKFORCE

Skilled up and well-trained, St. Louis’ workforce benefits from our extensive educational market

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EDUCATED & READY

Each year, 40 colleges and universities award 24,000 degrees, with 40% of the workforce holding a bachelor’s degree or higher.

STEM SAVVY

St. Louis boasts one of the largest STEM workforces in the U.S.; STEM employment here is 6% of total employment.

HIGHLY SKILLED

Forty-thousand students are enrolled annually in our regional two-year, community college, and tech programs.

REASONS TO RELOCATE OR EXPAND

COSTS AND INCENTIVES

Cost-competitive returns on your regional investment.

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INFRASTRUCTURE

Make the most of our robust trade, transportation, and warehousing sector

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STARTUP ECOSYSTEM

Support, Funding and Space for New Businesses to Thrive

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THE RIGHT REAL ESTATE

Whether you’re looking for a sprawling warehouse or a heavy-duty data center, flexible office space or multi-modal harbor access, the Greater St. Louis area offers a wide range of competitively priced real estate options.

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HOME BASE FOR BUSINESS

The St. Louis region’s diversified economy helps both corporate headquarters and major business divisions feel at home across a wide range of industries.

15
FORTUNE 1000

HEADQUARTERS

7
FORTUNE 500

HEADQUARTERS

8
FORBES LARGEST

U.S Private companies

OUR REGION’S ENGINES OF GROWTH

Fortune 500 companies and small businesses thrive here.

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Food & Beverage

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Plant Science

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Aerospace

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Geospatial

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Neuroscience

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Pharmaceuticals

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Medical Devices

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Chemical Manufacturing

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Machinery & Equipment

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Transportation

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Financial & Insurance

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Corporate Operations

Photo courtesy of Danforth Plant Science Center

STL - airplane - LHR in red above stylized St. Louis and London skylines with text Connecting St. Louis to the World

St. Louis Secures New Nonstop Flights to London

British Airways has announced flights between St. Louis Lambert International Airport and London’s Heathrow Airport beginning in April 2026.

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Aerial view of a large rectangular building with central courtyard, glass entrance, parking garages and a curved pond.

Now Open, NGA St. Louis Launches Next Phase of Geospatial Growth

The St. Louis region advances as a national leader, using geospatial technology to solve some of the world’s most pressing challenges.

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MEET OUR TEAM

Find the right contact.

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Ready to Get Started?

If you’re looking to consolidate, expand or move, we can help.

Contact Us

Tom Cirrito
We are thrilled to expand our footprint in St. Louis. This city offers a diverse and educated workforce, world-class research institutions such as Washington University in St. Louis, and an entrepreneurial spirit that make it an ideal home for Varro’s growth.
Tom Cirrito
Ph.D., Co-Founder and CEO, Varro Life Sciences